AFRIMS Armed Forces Research Institute of Medical Sciences
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Left navigator bar NewComer Information Check E-mail Hman Subjects Protection Information Management Resource Management Research Support Logistics Library Epidemiology and Disease Surveillance Human Resources Veterinary Medicine Virology Embassy of the United States, Bangkok Retrovirology JUSMAG Immunology Entomology Enteric Diseases AKO (Army Knowledge Online) Senior NCO RTA-AFRIMS WHO Collaborating Center Director WRAIR iSalute

Mission:  To identify vector- and rodent-borne disease threats of military and global health importance and to develop and evaluate interventions and products in order to mitigate those threats.

Vector Biology, Surveillance, and Control Research:  Develops and evaluates mosquito surveillance traps.  Evaluates control or preventive measures including insecticide barrier treatments, insecticide-impregnated bed nets and tents, and personal-use and spatial repellents.  Studies are aimed at understanding basic vector biology and behavior through vector competence and oviposition assays. Taxonomic keys are continually developed and updated for the mosquitoes of  Thailand .
Malaria Research: Conducts research on malaria biology and transmission.   On-going research includes studies on malaria parasite development in liver cells and mosquitoes and the establishment of an in vitro  system to screen antimalarial compounds and vaccines against exoerythrocytic, gametocytic and sporogonic stages of malaria parasites.  Studies are also focused on gametocytogenesis in Plasmodium falciparum  and P. vivax  and the production of different stages of human and animal malaria parasites in order to support drug and vaccine development and transmission blocking strategies.
Ectoparasitic and Zoonotic Disease Research: A one-of-a-kind Orientia tsutsugamushi -infected Leptotrombidium mite colony and a chigger challenge mouse model form the basis for studies on vector-pathogen interactions, scrub typhus transmission and immunology and evaluations of candidate scrub typhus vaccines. Research is also focused on designing more effective surveillance techniques for scrub typhus vectors. Our team of veterinarians and field mammalogists conduct epidemiological and ecological studies that are aimed at better understanding the distribution and variation of vectors and their related pathogens in animal hosts.
Vector-borne and Zoonotic Disease Diagnostics Program: Develops and evaluates rapid field assays for the detection of relevant pathogens.  Conducts cutting edge bioinformatics and molecular research on arthropod-borne disease vectors and pathogens.  Pathogens include, but are not limited to, dengue and chikungunya viruses, malaria parasites, and Orientia tsutsugamushi. 
GIS and Spatial-temporal Analysis of Vector-borne and Zoonotic Diseases: Applies Geographic Information Systems (GIS) -based tools to evaluate the risk of vector-borne disease outbreaks.  This capability incorporates environmental factors and field collection data (i.e. vector/pathogen distributions) in order to delineate vector-borne disease (i.e. dengue, chikungunya, Japanese encephalitis, malaria) risk areas.  
Personnel/Facilities: The Department of Entomology consists of approximately 50 full time employees to include 8 PhD scientists, and more than one dozen M.S. -level researchers.  A state-of-the-art Insectary supports the production of at least 6 different mosquito species for Plasmodium and arboviral transmission studies, behavioral studies, and dengue vaccine studies.  Additionally, the department maintains seven species of Leptotrombidium mites.  While the department conducts its research throughout  Thailand   and other parts of Asia ( South Korea China   and the  Philippines ), it maintains two field sites: one in Mae Sot (along the Thai-Myanmar border) and one in Kamphaeng Phet (located approximately 4 hrs north of Bangkok )

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Recent Activities at AFRIMS
AFRIMS recent activities HIV Vaccine Study First to show effectiveness AFRIMS on Dengue at Voice of America AFRIMS on Malaria in New York Times AFRIMS researchers instructed 104 medical cadets from Phramongkutklao College of Medicine AFRIMS hosts infectious diseae surveillance workshop for laos PDR lab technicians AFRIMS concludes Pilat Malaria Prophylaxis clinical trial in Cambodia Dr. Rampa Rattanarathiul received the Belkin Award, The highest honor given by the AMCA Dedication and opening of joint AFPMC AFRIMS molecular laboratory in the Phillippines NBC shows story on drug resistant malaria on the Thai-Cambodia border in Cambodia Malaria Vaccine: Inside look at first human trial from BBC news HVRC opening ceremony Change of Command 2015 AFRIMS leaders join "Bike For Mom 2015" event US Embassy Employee of the Month Public Release of Joint Concept of Health Services Public Release of Joint Concept of Health Services more AFRIMS activities